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  • Official site of Ambien CR, a dual-layer prescription sleep aid for the treatment of insomnia. Register for a free 7 night trial and $100 in cost savings.

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  • Ambien (zolpidem) is a sedative and is used for the short-term treatment of insomnia by helping you fall asleep. Includes Ambien side effects, interactions and indications.

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  • Some trade names of zolpidem are Ambien, Hypnogen, Myslee. Nimadorm, Nitrest, Sanval, Stilnoct, Stilnox, Zoldem (HEXAL AG), Zolfresh, and Zolt. Its hypnotic effects are similar to those ...

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  • Ambien CR (zolpidem tartrate extended release) is different from Ambien (zolpidem tartrate) in that the medication is formulated in a 2 layer tablet.

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  • Learn about the prescription medication Ambien (Zolpidem Tartrate), drug uses, dosage, side effects, drug interactions, warnings, and patient labeling.

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  • News reports began to surface last week concerning a rather bizarre phenomenon referred to as &#8243;Ambien sleepwalking&#8243; in which people find themselves in a virtual &#8243;

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  • Learn about common side effects of AMBIEN CR ... All medicines have side effects. When taking a medication such as AMBIEN CR, you want the benefits to outweigh the risks.

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  • A place for people to post about Ambien side effects. Read Ambien patient comments or post your own.

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  • Am·bi·en (m b-n) A trademark for the drug zolpidem tartrate. zolpidem tartrate. Ambien, Ambien CR, Stilnoct (UK), Tovalt ODT. Pharmacologic class: Imidazopyridine

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  • What is Ambien (Zolpidem)? Zolpidem is a sedative, also called a hypnotic. It affects chemicals in your brain that may become unbalanced and cause sleep problems (insomnia).

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Amy Sedaris Ambien Incident Thankyou Ambien. Ambien

Zolpidem
Systematic (IUPAC) name
N,N,6-trimethyl-2-(4-methylphenyl)-
imidazo(1,2-a)pyridine-3-acetamide
Identifiers
CAS number82626-48-0
ATC codeN05CF02
PubChem5732
DrugBankAPRD00095
ChemSpider5530
Chemical data
FormulaC19H21N3O 
Mol. mass307.395 g/mol
SMILESeMolecules & PubChem
Pharmacokinetic data
Bioavailability70% (oral) 92% bound in plasma
MetabolismHepatic CYP34A
Half life2 to 2.6 hours
Excretion56% renal
34% fecal
Therapeutic considerations
Pregnancy cat.

B3(AU) B(US)

Legal status

Schedule IV(US) Class C / POM (UK)

RoutesOral

Zolpidem is a prescription medication used for the short-term treatment of insomnia, as well as some brain disorders. It is a short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to gamma-aminobutyric acid (GABAA) receptors at the same location as benzodiazepines. It works quickly (usually within 15 minutes) and has a short half-life (2–3 hours). Trade names of zolpidem include Ambien, Ambien CR, Ivedal, Nytamel, Stilnoct, Stilnox, Zoldem, Zolnod and Zolpihexal.

Its hypnotic effects are similar to those of the benzodiazepine class of drugs, but it is molecularly distinct from the classical benzodiazepine molecule and is classified as an imidazopyridine. Flumazenil, a benzodiazepine receptor antagonist, which is used for benzodiazepine overdose, can also reverse zolpidem's sedative/hypnotic and memory impairing effects.

As an anticonvulsant and muscle relaxant, the beneficial effects start to emerge at 10 and 20 times the dose required for sedation, respectively. For that reason, it has never been approved for either muscle relaxation or seizure prevention. Such drastically increased doses are more inclined to induce one or more negative side-effects, including hallucinations and/or amnesia. (See below.)

The patent 4382938 in the United States on zolpidem was held by the French pharmaceutical corporation Sanofi-Aventis. On April 23, 2007 the U.S. FDA approved 13 generic versions of zolpidem tartrate. Zolpidem is available from several generic manufacturers in the UK, as a generic from Sandoz in South Africa, as well as from other manufacturers such as Ratiopharm.

Recently, zolpidem has been cited in various medical reports mainly in the United Kingdom as waking persistent vegetative state (PVS) patients, and dramatically improving the conditions of people with brain injuries.

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About Ambien

Amy Sedaris Ambien Incident
ZolpidemSystematic (IUPAC) nameN,N,6-trimethyl-2-(4-methylphenyl)-imidazo(1,2-a)pyridine-3-acetamideIdentifiersCAS number82626-48-0ATC codeN05CF02PubChem5732DrugBankAPRD00095ChemSpider5530Chemical dataFormulaC19H21N3O Mol. mass307.395 g/molSMIL... Read more
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  • Ambien (Stilnox, Zolpidem) is in a class of drugs called sedative/hypnotics or sleep medicines. Stilnox (the brandname used for Ambien outside the US) affects chemicals in your brain that may become unbalanced and cause insomnia. Ambien (Stilnox, Zolpidem) induces sleep and causes relaxation. It is used to treat sleep disorders such as trouble fall


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