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  • Lip·i·tor (l p-tôr) A trademark for the drug atorvastatin calcium. atorvastatin calcium. Lipitor. Pharmacologic class: HMG-CoA reductase inhibitor. Therapeutic class: Lipid ...

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  • Lip·i·tor   (l p-t r, -tôr) A trademark used for the drug atorvastatin. Thesaurus Legend: Synonyms Related Words Antonyms. Noun: 1. Lipitor - an oral drug (trade name Lipitor ...

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Lipitor at Canada Pharmacy: Canada Drugs Pharmacy Lipitor Does More Swedish packet for Lipitor tablets

Atorvastatin
Systematic (IUPAC) name
-2-(4-fluorophenyl)-beta, delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4- -1H- pyrrole-1-heptanoic acid
Identifiers
CAS number134523-00-5
ATC codeC10AA05
PubChem60823
DrugBankAPRD00055
Chemical data
FormulaC33H35FN2O5 
Mol. mass558.64
SMILESeMolecules & PubChem
Pharmacokinetic data
Bioavailability12%
MetabolismLiver
Half life14 hours
ExcretionBile
Therapeutic considerations
Pregnancy cat.

D(AU) X(US)

Legal status

Prescription Only (S4)(AU) POM(UK) ℞-only(US)

Routesoral

Atorvastatin (INN) (pronounced /əˌtɔrvəˈstætən/), (marketed under the name Lipitor®, Lipidra, Aztor, Torvatin, Sortis, Torvast, Torvacard, Totalip, Tulip, Xarator, Atorpic, Liprimar, Atorlip, Avas, Storvas and other names), is a member of the drug class known as statins, used for lowering blood cholesterol. Atorvastatin inhibits the rate-determining enzyme located in hepatic tissue that produces mevalonate, a small molecule used in the synthesis of cholesterol and other mevalonate derivatives. This lowers the amount of cholesterol produced which in turn lowers the total amount of LDL cholesterol.

Atorvastatin was first synthesized in 1985 by Bruce Roth while working at Warner-Lambert Company (now Pfizer).

With 2006 sales of US$12.9 billion under the brand name Lipitor, it is the largest selling drug in the world.

Lipitor is not the only statin; there are several other statins on the market.

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About Lipitor

AtorvastatinSystematic (IUPAC) name-2-(4-fluorophenyl)-beta, delta-dihydroxy-5- (1-methylethyl)-3-phenyl-4- -1H- pyrrole-1-heptanoic acidIdentifiersCAS number134523-00-5ATC codeC10AA05PubChem60823DrugBankAPRD00055Chemical dataFormulaC33H35FN2O5 ... Read more

Lipitor related Videos
Recent talks about Lipitor
  • Sales of Pfizer’s blockbuster drugs Lipitor and Chantix have dropped considerably compared to 2007, but the company was still able to beat its earnings estimate.


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  • Lipitor is used with diet changes (restriction of cholesterol and fat intake) to reduce the amount of cholesterol and certain fatty substances in your blood.


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